Effects of green tea polyphenol on cognitive and acetylcholinesterase activities |
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| Authors: | Kim Hye Kyung Kim Mija Kim Sunki Kim Mujo Chung Joo Ho |
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| Institution: | Department of Food and Biotechnology, Hanseo University, Seosan, Korea. hkkim111@hanseo.ac.kr |
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| Abstract: | The effect of tea polyphenol (TP) on cognitive and anti-cholinesterase activity was examined in scopolamine-treated mice. Chronic administration of TP significantly reversed scopolamine-induced retention deficits in both step-through passive avoidance and spontaneous alternation behavior tasks. Furthermore, TP exhibited a dramatic inhibitory effect on acetylcholinesterase activity. This finding suggests that TP might be useful in the treatment of Alzheimer's disease. |
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