An Evidence for the Repair of Double-Strand Scissions in DNA of Micrococcus radiodurans after Alpha Bombardment |
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| Authors: | Shigeru Kitayama Takashi Karasawa Akira Matsuyama |
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| Institution: | The Institute of Physical and Chemical Research, Yamato-machi, Saitama Prefecture, Japan |
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| Abstract: | The conversion of prochaetoglobosins as plausible precursors into mycotoxin chaetoglobosin A (1) in a cell-free system of Chaetomium subaffine was unsuccessful. However, reductase activity of the 20-keto-analogues (1), and prochaetoglobosins II (5) and III (6) were found in a microsomal fraction of this fungi. Two new metabolites of chaetoglobosins, named chaetoglobosin Fex (2) and 20-dihydro-chaetoglobosin A (3), were also isolated from the same micro-organisms. Their structures were elucidated by spectroscopic data and chemical transformation. |
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| Keywords: | inulin Bacillus sp snu-7 di-D-fructose 1 2′:2 3′ dianhydride IFTase (DFA III-producing) |
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