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RNA structure, metal ions, and catalysis
Authors:Scott W G
Institution:Department of Chemistry and Biochemistry, Sinsheimer Laboratories, The Center for the Molecular Biology of RNA, University of California at Santa Cruz, Santa Cruz, 95064, USA. wgs@kropotkin.ucsc. edu.
Abstract:Several new and unexpected insights into the metalloenzymology of ribozymes have been achieved in the past year. From a mechanistic point of view, the NMR and crystal structures of a small Pb(2+)-dependent ribozyme have been particularly revealing.
Keywords:RNA structure  HDV ribozyme  Leadzyme  VS ribozyme  Catalytic RNA
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