He–Ne laser (632.8 nm) pre‐irradiation gives protection against DNA damage induced by a near‐infrared trapping beam |
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| Authors: | Khageswar Sahu Samarendra Kumar Mohanty Pradeep Kumar Gupta |
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| Institution: | 1. Laser Biomedical Applications and Instrumentation Division, Raja Ramanna Centre for Advanced Technology, Indore‐452013, India;2. Presently at: Beckman Laser Institute, University of California, Irvine, CA 92612, USA |
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| Abstract: | We report the results of a study carried out to investigate the effect of He–Ne laser (632.8 nm) pre‐irradiation on DNA damage induced by continuous wave 1064 nm trapping beam exposure in MCF‐7 cells. A significant decrease in % tail DNA (p < 0.05) was observed in MCF‐7 cells pre‐exposed to He–Ne laser beam. The dependence of the induced protection against 1064 nm trapping beam irradiation induced DNA damage on the time interval between the two irradiations as well as the He–Ne laser pre‐irradiation parameters is presented. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim) |
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| Keywords: | Optical tweezers DNA damage Comet Assay Low‐level light effect |
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