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Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discovery |
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| Authors: | Donna D Yu Wenwei Lin Taosheng Chen Barry M Forman |
| Institution: | 1. Department of Diabetes, Endocrinology and Metabolism, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA;2. Department of Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA |
| Abstract: | |
| Keywords: | FXR"} {"#name":"keyword" "$":{"id":"k0010"} "$$":[{"#name":"text" "_":"farnesoid X receptor NRs"} {"#name":"keyword" "$":{"id":"k0020"} "$$":[{"#name":"text" "_":"nuclear receptors HTS"} {"#name":"keyword" "$":{"id":"k0030"} "$$":[{"#name":"text" "_":"high-throughput screen LBD"} {"#name":"keyword" "$":{"id":"k0040"} "$$":[{"#name":"text" "_":"ligand-binding domain TR-FRET"} {"#name":"keyword" "$":{"id":"k0050"} "$$":[{"#name":"text" "_":"time resolved fluorescence resonance energy transfer |
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