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Inhibition of heparan sulphate and other glycosaminoglycans binding to Helicobacter pylori by various polysulphated carbohydrates |
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| Authors: | Siiri Hirmo Meeme Utt Martina Ringner Torkel Wadström |
| Institution: | University of Lund, Institute of Medical Microbiology, Sölvegatan 23, S-223 62 Lund, Sweden |
| Abstract: | Abstract Heparan sulphate binding to Helicobacter pylori at pH 4 to 5 was inhibited with various sulphated polysaccharides (heparin and chondroitin sulphates, fucoidan, carrageenans and some others), but not by carboxylated or nonsulphated compounds. Heparin binding proteins are exposed on the cell surface. |
| Keywords: | Helicobacter pylori Heparin binding protein Heparan sulphate binding protein Sulphated glycosaminoglycan |