Observation on a 65-kilodalton protein isolated from kanagawa positive strains of Vibrio parahaemolyticus |
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| Authors: | B L Sarkar R Kumar S P De S C Pal |
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| Institution: | National Institute of Cholera and Enteric Diseases, Calcutta, India. |
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| Abstract: | Crude hemolysin from four KP+ strains of Vibrio parahaemolyticus belonging to serotype 02:K3 exhibited a major protein band (molecular weight, 65 kilodaltons (kDa] in addition to a previously known thermostable direct hemolysin band (molecular weight, 21 kDa) in SDS - polyacrylamide slab gel electrophoresis. These strains showed maximum virulence leading to 100% mouse lethality within 2-6 h. It is hypothesized that this 65-kDa protein may play a vital role in the pathogenesis of the disease caused by V. parahaemolyticus. |
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