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Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations |
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| Authors: | Guillaume A Schoch |
| Institution: | F. Hoffmann-La Roche Ltd., Pharma Research, Discovery Technologies, Grenzacherstrasse 124, CH-4070 Basel, Switzerland |
| Abstract: | |
| Keywords: | GR glucocorticoid receptor PR progesterone receptor NR nuclear hormone receptor LBD ligand binding domain NCoR nuclear receptor corepressor PDB Protein Data Bank GST glutathione S-transferase TCEP tris(2-carbohyethyl)phosphine |
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