类芒齿黄芪地下部分化学成分研究

为了解类芒齿黄芪( Astragalus camptodontoides)主要化学成分，从其地下部分甲醇提取物的乙酸乙酯部位分离出19个单体化合物，通过现代波谱分析及理化性质等手段分别鉴定为异补骨脂黄酮(1)，4′-hydroxy-isolonchocarpin (2)，5-去氧山豆根黄酮(3)，shinflavanone (4)，khonklonginols H (5)，4′-O-methylpreglabridin (6)，3′-hydroxy-4′-O-methylglabridin (7)，4′-O-methylglabridin (8)，8-prenyl-phaseollinisoflavan (9)，xambioona (10)，光甘草酚(11)，粗毛甘草素H (12)，methylnissolin (13)，邻苯二甲酸异丁酯(14)，邻苯二甲酸丁酯异丁酯(15)，β-谷甾醇(16)，胡萝卜苷(17)，齐墩果酸(18)，(2S，3S，4R，9E)-1，3，4-trihydroxy-2-(2′R)-2′- hydr-oxytetraco-sanoylamino]-9-octadecene (19)。化合物1~19均为首次从该植物中获得，化合物1~7为首次从黄芪属(Astraga-lus)植物中分离得到。

Chemical constituents from underground part of Astragalus camptodontoides

For understanding the chemical constituents of Astragalus camptodontoides, nineteen compounds were isolated from the ethyl acetate fraction of the methanol extract of underground part. By physical-chemical properties and spectro-scopic date, their structures were identified as isobavachin (1), 4′-hydroxyisolonchocarpin (2), 5-deoxyeuchrenone ( 3) , shinflavanone ( 4) , khonklonginols H ( 5) , 4′-O-methylpreglabridin ( 6) , 3′-hydroxy-4′-O-methylglabridin ( 7) , 4′-O-methylglabridin ( 8) , 8-prenyl-phaseollinisoflavan ( 9 ) , xambioona ( 10 ) , glabrol ( 11 ) , glyasperin H ( 12 ) , methylnissolin ( 13) , phthalic acid isodibutyl ester ( 14) , butul isobutyl phthalate ( 15) ,β-sitosterol ( 16) , daucosterol (17), oleanic acid (18), and (2S,3S,4R,9E)-1,3,4-trihydroxy-2-(2′R)-2′-hydroxytetracosanoylamino]-9-octade-cene (19). All compounds were isolated from this plant for the first time, including compounds 1-7 obtained from Astragalus genus for the first time.