| 量子点在新药开发中的应用 |
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| 引用本文： | 谭君,祝连彩.量子点在新药开发中的应用[J].生命的化学,2008,28(6). |
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| 作者姓名： | 谭君 祝连彩 |
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| 作者单位： | 1. 重庆大学生物工程学院,重庆,400030;重庆教育学院生命科学与化学系,重庆,400067
2. 重庆大学生物工程学院,重庆,400030 |
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| 基金项目： | 重庆市教委科学技术研究项目
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重庆市自然科学基金项目
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| 摘 要： | 由于具有优异的光学特性,量子点在生物医学领域内的研究和应用取得了一些有意义的进展,同时也引起了新药开发人员的兴趣.本文概述了量子点在新药开发中所具有的优势,分析了量子点在药物传输、药物筛选和药靶确证方面的潜在应用,进一步讨论了当前量子点应用于新药开发存在的问题和不足.
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| 关 键 词： | 量子点 新药开发 药物传输 药物筛选 药靶确证 |
Application of quantum dots in drug discovery |
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| Jun TAN,Lian-Cai ZHU.Application of quantum dots in drug discovery[J].Chemistry of Life,2008,28(6). |
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| Authors: | Jun TAN Lian-Cai ZHU |
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| Institution: | Jun TAN 1,2 Lian-Cai ZHU1 (1Bioengineering College,Chongqing University,Chongqing 400030,China,2Department of Life Science & Chemistry,Chongqing Education College,Chongqing 400067,China) |
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| Abstract: | Because of excellent optical properties, quantum dots (QDs) have gained some meaningful progress in biomedical research and application, and have caught great interests of researchers who are engaged in drug discovery. In this paper, we mainly reviewed the characteristics of quantum and its potential applications in drug delivery, drug screening and drug target identification. Furthermore, the problems and limitations of quantum dots in drug discovery, such as biocompatibility, bioconjugation and biotoxicit... |
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| Keywords: | quantum dot drug discovery drug delivery drug screening drug target identification |
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