| 生长因子诱导人脐带/胎盘间充质干细胞定向分化 |
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| 引用本文： | 张嘉萱,周向荣,刘秋英,王一飞.生长因子诱导人脐带/胎盘间充质干细胞定向分化[J].生命的化学,2010(6). |
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| 作者姓名： | 张嘉萱 周向荣 刘秋英 王一飞 |
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| 作者单位： | 广州(暨南)生物医药研究开发基地;亚太干细胞科研中心有限公司; |
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| 基金项目： | 国际科技合作项目(2008DFA30590); 广州(暨南)-香港细胞工程联合实验室项目资助 |
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| 摘 要： | 近年来,间充质干细胞(mesenchymal stem cell,MSC)已成为干细胞领域的研究热点,其不仅支持造血系统,还可在特定的培养条件下向多种组织细胞分化。人脐带和胎盘来源的MSC取材容易,较骨髓间充质干细胞有更广泛的应用前景。本文就含有特定生长因子的培养基诱导人脐带MSC和人胎盘MSC定向分化的研究进展作一简要的综述。
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| 关 键 词： | 人脐带间充质干细胞 人胎盘间充质干细胞 生长因子 分化 |
Research progress of growth factor inducing the directed differentiation of human umbilical cord-derived or human placenta-derived MSCs |
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| Jia-Xuan Zhang,Xiao-Rong Zhou,Qiu-Ying Liu,Yi-Fei Wang Guangzhou Jinan Biomedicine Research & Development Center,Guangzhou ,China,Asia Pacific Stem Cell Science Limited,HongKong,Chin.Research progress of growth factor inducing the directed differentiation of human umbilical cord-derived or human placenta-derived MSCs[J].Chemistry of Life,2010(6). |
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| Authors: | Jia-Xuan Zhang Xiao-Rong Zhou Qiu-Ying Liu Yi-Fei Wang Guangzhou Jinan Biomedicine Research & Development Center Guangzhou China Asia Pacific Stem Cell Science Limited HongKong Chin |
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| Institution: | Jia-Xuan Zhang1,Xiao-Rong Zhou2,Qiu-Ying Liu1,Yi-Fei Wang1 1Guangzhou Jinan Biomedicine Research & Development Center,Guangzhou 510632,China,2Asia Pacific Stem Cell Science Limited,HongKong,Chin |
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| Abstract: | In recent years,mesenchymal stem cells(MSCs) have become a research hotspot in the stem cell area,which can not only support hematopoietic system,but also differentiate into lineages of tissue cells under a certain culture condition.Human umbilical cord-derived and human placenta-derived MSCs are easily available,which have more widespread application prospect than bone marrow-derived MSCs.The paper makes a brief review on culture medium which contains specific growth factor inducing directed differentiatio... |
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| Keywords: | human umbilical cord-derived mesenchymal stem cell(hUBMSC) human placenta-derived mesenchymal stem cell(hPMSC) growth factor differentiation |
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