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LTR retrotransposons and the evolution of dosage compensation in <Emphasis Type="Italic">Drosophila</Emphasis>
Authors:Lilya V Matyunina  Nathan J Bowen  John F McDonald
Institution:(1) School of Biology and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332, USA
Abstract:

Background  

Dosage compensation in Drosophila is the epigenetic process by which the expression of genes located on the single X-chromosome of males is elevated to equal the expression of X-linked genes in females where there are two copies of the X-chromosome. While epigenetic mechanisms are hypothesized to have evolved originally to silence transposable elements, a connection between transposable elements and the evolution of dosage compensation has yet to be demonstrated.
Keywords:
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