国内医院转化医学发展动态分析

从机构建设和科学研究两个角度分析国内医院转化医学发展现状。机构建设方面，美国转化医学中心的依托单位多为大学，组织架构较完善。但国内的依托单位多为医院或临床中心，较为分散，多为自发成立，缺乏国家层面的规划部署，难以形成比较高效的转化医学研究体系。但机构建设的迅速发展带来了转化研究成果的增多。国内转化医学研究多为从基础医学的角度探索疾病的致病机制和干预措施，如将实验室技术、细胞生物学、生物化学与分子生物学、药理学、应用生物技术等和临床问题的整合，特别是肿瘤、心血管病、内分泌与代谢病、消化系与腹部疾病等临床领域的转化研究受到了国内较多的关注。最后提出国内医院转化医学发展的策略和建议。

Dynamic Analysis of Translational Medicine Development of in Hospitals in China

The development of translational medicine in hospitals in China is analyzed from the perspectives of both institutional construction and translational research. From the point view of institutional construction, Translational Medicine Centers in US, mostly relies on universities, so they have more perfect organizational structure. But in China, most of them are established in hospitals or clinical centers, and are more dispersed and spontaneously formed. Due to the lack of national-level planning, it is difficult to form a more efficient translational medicine research system. But the rapid development of translational medicine institutions has brought an increase of research output in translational research. Domestic translational medical research mostly explores the pathogenesis and interventions of diseases from the basic research, that is, the integration between clinical issues and laboratory techniques, cell biology, biochemistry and molecular biology, pharmacology, and applied biotechnology. Translational research in oncology, cardiovascular disease, endocrine and metabolic diseases, digestive and abdominal diseases has brought more attention in China. Finally strategies and recommendations on the development of translational medicine in hospitals are proposed.