Glycosphingolipids of normal and leukemic human leukocytes |
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| Authors: | Bruce A Macheri William M F Lee Mary Alice Westrick |
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| Institution: | (1) Cancer Research Institute, Dept. of Medicine, University of California, 94143 San Francisco, CA, USA;(2) Dept. of Pharmaceutical Chemistry, University of California, 94143 San Francisco, CA, USA |
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| Abstract: | Summary We have reviewed the studies on neutral glycosphingolipids and gangliosides of normal and leukemia human leukocytes. In this review, we examine (a) the glycosphingolipid composition of various leukocyte populations, (b) the differences in glycosphingolipids found among subsets of these cells, (c) the possible use of these compounds as markers of differentiation, and (d) the changes in glycosphingolipid composition that occur with leukemogenesis. |
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