| 三七环二肽成分和人参内酰胺成分 |
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| 引用本文： | 谭宁华,王双明,杨亚滨,何敏.三七环二肽成分和人参内酰胺成分[J].云南植物研究,2003,25(3):366-368. |
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| 作者姓名： | 谭宁华 王双明 杨亚滨 何敏 |
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| 作者单位： | 1. 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南,昆明,650204
2. 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南,昆明,650204;天津天士力制药集团有限公司药物研究所,天津,300142 |
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| 基金项目： | This work was supported by grants from the National Natural Science Fundation of China (39500182) and Natural Science Fund of Yunnan Province (95C088Q) |
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| 摘 要： | From the roots of Panax notoginseng fourteen cyclodipeptides 1-14 were isolated including one new compound (1),seven new natural compounds (4-10) and six known compounds (2-3,11-14) together with one known other compound 15.The chemical structure of 1 was elucidated as cyclo-(Leu-Thr) based on spectral methods.From the roots of Panax ginseng five known lactams (16-20) includingpyrng lutamic acid were isolated together with butyric diacid,daucosterol and sucrose.The primary binactivity test showed that pyroglutamic acid and its n-butyl derivative have weak Ca^2 antagonistic activity.
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| 关 键 词： | 三七 人参 五加科 环二肽 内酰胺 |
| 文章编号： | 0253-2700(2003)03-0366-03 |
| 修稿时间： | 2002年11月3日 |
Cyclodipeptides of Panax notoginseng and Lactams of Panax ginseng |
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| TAN Ning-Hua,WANG Shuang-Ming ,YANG Ya-Bin,HE Ming.Cyclodipeptides of Panax notoginseng and Lactams of Panax ginseng[J].Acta Botanica Yunnanica,2003,25(3):366-368. |
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| Authors: | TAN Ning-Hua WANG Shuang-Ming YANG Ya-Bin HE Ming |
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| Institution: | TAN Ning-Hua1,WANG Shuang-Ming 1,2,YANG Ya-Bin1,HE Ming1 |
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| Abstract: | From the roots of Panax notoginseng fourteen cyclodipeptides 1-14 were isolated including one new compound (1),seven new natural compounds (4-10) and six known compounds (2-3,11-14) together with one known other compound 15.The chemical structure of 1 was elucidated as cyclo-(Leu-Thr) based on spectral methods.From the roots of Panax ginseng five known lactams (16-20) including pyroglutamic acid were isolated together with butyric diacid,daucosterol and sucrose.The primary bioactivity test showed that pyroglutamic acid and its n-butyl derivative have weak Ca 2+ antagonistic activity. |
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| Keywords: | Panax notoginseng Panax ginseng Araliaceae cyclodipeptides lactams |
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