The function of communities in protein interaction networks at multiple scales |
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| Authors: | Anna CF Lewis Nick S Jones Charlotte M Deane |
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| Institution: | (1) Department of Statistics, University of Oxford, Oxford, UK;(2) Department of Physics, University of Oxford, Oxford, UK;(3) CABDyN Complexity Centre, University of Oxford, Oxford, UK;(4) Department of Biochemistry, University of Oxford, Oxford, UK;(5) Oxford Centre for Integrative Systems Biology, University of Oxford, Oxford, UK;(6) Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, UK |
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| Abstract: | Background If biology is modular then clusters, or communities, of proteins derived using only protein interaction network structure
should define protein modules with similar biological roles. We investigate the link between biological modules and network
communities in yeast and its relationship to the scale at which we probe the network. |
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