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Targeted inhibition of ACK1 can inhibit the proliferation of hepatocellular carcinoma cells through the PTEN/AKT/mTOR pathway |
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| Authors: | Bin Wang Kai Song Lihong Chen Hongying Su Lingyun Gao Jingfeng Liu Aimin Huang |
| Institution: | 1. Department of Pathology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, China
Department of Pathology, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, Fujian, China Institute of Oncology, Fujian Medical University, Fuzhou, Fujian, China Diagnostic Pathology Center, Fujian Medical University, Fuzhou, Fujian, China;2. Department of Pathology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, China Department of Pathology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China;3. Department of Pathology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, China Institute of Oncology, Fujian Medical University, Fuzhou, Fujian, China Diagnostic Pathology Center, Fujian Medical University, Fuzhou, Fujian, China;4. Department of Pathology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, China Department of Pathology, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, Fujian, China;5. Department of Hepatopancreatobiliary Surgery, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, Fujian, China Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China;6. Department of Pathology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, China |
| Abstract: | |
| Keywords: | activated Cdc42-associated kinase 1 AIM-100 apoptosis Dasatinib hepatocellular carcinoma PTEN/AKT/mTOR signalling pathway |