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High variability and non-neutral evolution of the mammalian <Emphasis Type="Italic">avpr1a</Emphasis> gene
Authors:Sabine Fink  Laurent Excoffier  Gerald Heckel
Institution:(1) Computational and Molecular Population Genetics (CMPG), Zoological Institute, University of Bern, Baltzerstrasse 6, CH-3012 Bern, Switzerland
Abstract:

Background  

The arginine-vasopressin 1a receptor has been identified as a key determinant for social behaviour in Microtus voles, humans and other mammals. Nevertheless, the genetic bases of complex phenotypic traits like differences in social and mating behaviour among species and individuals remain largely unknown. Contrary to previous studies focusing on differences in the promotor region of the gene, we investigate here the level of functional variation in the coding region (exon 1) of this locus.
Keywords:
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