Evolution of ribonuclease H genes in prokaryotes to avoid inheritance of redundant genes |
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Authors: | Hiromi Kochiwa Masaru Tomita Akio Kanai |
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Institution: | (1) Institute for Advanced Biosciences, Keio University, 997-0017 Tsuruoka, Japan;(2) Systems Biology Program, Graduate School of Media and Governance, Keio University, 252-8520 Fujisawa, Japan |
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Abstract: | Background A theoretical model of genetic redundancy has proposed that the fates of redundant genes depend on the degree of functional
redundancy, and that functionally redundant genes will not be inherited together. However, no example of actual gene evolution
has been reported that can be used to test this model. Here, we analyzed the molecular evolution of the ribonuclease H (RNase
H) family in prokaryotes and used the results to examine the implications of functional redundancy for gene evolution. |
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