A general scenario of Hox gene inventory variation among major sarcopterygian lineages |
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Authors: | Dan Liang Riga Wu Jie Geng Chaolin Wang and Peng Zhang |
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Institution: | (1) State Key Laboratory of Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-Sen University, 510275 Guangzhou, China;(2) Alligator Research Center of Anhui Province, 242000 Xuanzhou, Anhui, China |
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Abstract: | Background
H ox genes are known to play a key role in shaping the body plan of metazoans. Evolutionary dynamics of these genes is therefore
essential in explaining patterns of evolutionary diversity. Among extant sarcopterygians comprising both lobe-finned fishes
and tetrapods, our knowledge of the Hox genes and clusters has largely been restricted in several model organisms such as frogs, birds and mammals. Some evolutionary
gaps still exist, especially for those groups with derived body morphology or occupying key positions on the tree of life,
hindering our understanding of how Hox gene inventory varied along the sarcopterygian lineage. |
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Keywords: | |
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