An aqueous fluorescent probe for Hg2+ detection with high selectivity and sensitivity |
| |
| Authors: | Qian Fang Qian Liu Xiangzhi Song Jian Kang |
| |
| Institution: | 1. College of Chemistry & Chemical Engineering, Central South University, Changsha, Hunan Province, Peoples Republic of China;2. College of Chemical Engineering and Modern Materials, Shangluo University, Shangluo, Shanxi Province, Peoples Republic of China;3. State Key Laboratory for Powder Metallurgy, Central South University, Changsha, Hunan Province, Peoples Republic of China;4. State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, Liaoning Province, Peoples Republic of China;5. The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, Peoples Republic of China |
| |
| Abstract: | An aqueous fluorescent probe, 1, was developed for the rapid detection of Hg2+ with high sensitivity and excellent selectivity. Upon the addition of Hg2+ in pure aqueous media, the Hg2+‐mediated hydrolysis of vinyl ether and subsequent cyclization reactions converted probe 1 into the corresponding iminocoumarin dye, which is strongly fluorescent when excited. The application of this probe for the detection of intracellular Hg2+ was successfully demonstrated in living cells. Copyright © 2015 John Wiley & Sons, Ltd. |
| |
| Keywords: | fluorescent probe Hg2+ hydrolysis reaction vinyl ether water‐soluble |
|
|
