Naked eye sensing of toxic metal ions in aqueous medium using thiophene‐based ligands and its application in living cells |
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Authors: | Duraisamy Udhayakumari Sivalingam Suganya Sivan Velmathi Davoodbasha MubarakAli |
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Institution: | 1. Organic and Polymer Synthesis laboratory, Department of Chemistry, National Institute of Technology, Tiruchirappalli, India;2. Central Inter‐Disciplinary Research Facility (CIDRF), Mahatma Gandhi Medical College and Research Institute Campus, Puducherry, India |
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Abstract: | Thiophene‐based diimine (R1) and monoimine (R2) were synthesized in a single step, and their cation binding affinity was tested using colorimetric and UV–vis spectral studies. R1 selectively shows a colorimetric turn‐on response for Pb2+, Hg2+ ions and colorimetric turn‐off with Sn2+ ions, and R2 shows visual response for Cu2+ and Hg2+ over other examined metal ions in aqueous medium. R1 forms 1:1 complex with Pb2+, Hg2+, and Sn2+ and exhibits fluorescence quenching, whereas R2 shows 2:1 complex with Hg2+, Cu2+ and shows fluorescence enhancement. The structural and electronic properties of the sensors and their metal complexes were also investigated using Density Functional Theory calculations. R2 was also successfully demonstrated as a fluorescent probe for detecting Cu2+ ions in living cells. Copyright © 2014 John Wiley & Sons, Ltd. |
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Keywords: | chromogenic sensor schiff base cation recognition aqueous medium DFT living cells |
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