Two New Isoprenylated Stilbenes from Artocarpus chama

Two new stilbenes with two isoprenoid groups, namely artostilbenes A (compound 1) and B (compound 2), were isolated from the stems of Artocarpus chama Buch.-Ham. by repeated column chromatography. Their structures were elucidated as (E)-4-2-(7-methoxy-2,2-dimethyl-6-(3-methylbut-2-enyl)-2H-1-benzopyran-5-yl)vinyl]benzene-1,2-diol (compound 1) and (Z)-4-2-(7-methoxy-2,2-dimethyl-6-(3-methylbut-2-enyl)-2H-1-benzopyran-5-yl)vinyl]benzene-1,2-diol (compound 2) by spectroscopic methods, mainly by 1D-, 2D-NMR and MS spectra. Compounds 1 and 2 are two cis- and trans-isomers and compound 2 is the first cis-stilbene isolated from Moraceous plants.