| 有机磷农药降解酶及其基因工程研究进展 |
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| 引用本文： | 伍宁丰,梁果义,邓敏捷,姚斌,范云六.有机磷农药降解酶及其基因工程研究进展[J].生物技术通报,2003(5):9-12. |
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| 作者姓名： | 伍宁丰 梁果义 邓敏捷 姚斌 范云六 |
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| 作者单位： | 1. 中国农业科学院生物技术研究所,北京,100081
2. 中国农业科学院饲料研究所,北京,100081 |
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| 摘 要： | 有机磷农药是国内外使用最广泛的农药之一，为农业丰收做出了很大贡献。但是，有机磷农药具有抑制人体乙酰胆碱酯酶的功能，对人存在着程度不同的毒性。有机磷农药降解酶可降解有机磷农药分子，破坏有机磷农药的磷酯键而使其脱毒。综述了有机磷农药降解酶及其特性，以及相关基因的分离克隆和基因工程研究进展。
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| 关 键 词： | 有机磷农药 降解酶 基因工程 磷酯键 |
The Development of the Research on Genetic Engineering of Organophosphorus Acid Hydrolase |
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| Wu Ningfeng,Liang Guoyi,Deng Minjie,Yao Bin,Fan Yunliu.The Development of the Research on Genetic Engineering of Organophosphorus Acid Hydrolase[J].Biotechnology Bulletin,2003(5):9-12. |
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| Authors: | Wu Ningfeng Liang Guoyi Deng Minjie Yao Bin Fan Yunliu |
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| Institution: | Wu Ningfeng 1 Liang Guoyi 1 Deng Minjie 1 Yao Bin 2 Fan Yunliu 1 |
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| Abstract: | Sythetic organophosphates(OPs) are used widely as insecticides in agriculture. Because these compounds are potent inhibitors of acetylcholinesterase, they are hazardous to human and animals. Organophosphorus acid hydrolase can break the phosphoester bonds to reduce the toxicity of OPs. This article reviews the research on the properties of organophosphorus acid hydrolase, and its gene isolation, cloning and genetic engineering. |
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| Keywords: | Organophosphates(OPs) Organophosphorus acid hydrolase Genetic engineering |
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