| 微生物发酵琥珀酸的研究进展 |
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| 引用本文： | 郑璞,孙志浩,倪晔,刘璇.微生物发酵琥珀酸的研究进展[J].生物技术通报,2008(Z1). |
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| 作者姓名： | 郑璞 孙志浩 倪晔 刘璇 |
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| 作者单位： | 江南大学生物工程学院教育部工业生物技术重点实验室,无锡,214122 |
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| 基金项目： | 国家863项目(No.2006AA02Z235);;江苏省自然科学基金前期预研项目(No.BK2005201) |
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| 摘 要： | 琥珀酸是一种重要的C_4平台化合物,生物基琥珀酸可作为合成大宗化学品的起始原料,在食品、医药、表面活性剂、洗涤剂、绿色溶剂、生物可降解塑料和动植物生长刺激物剂领域有广泛的应用前景。从可再生原料出发,发酵过程固定CO_2,使得微生物发酵生产琥珀酸具有良好的环境优势,成为近年研究的热点。围绕微生物发酵法生产琥珀酸迫切需要解决的主要问题,综述了国内外对琥珀酸生产菌的选育、其代谢机理与产酸条件、发酵过程工艺、产品提取等方面的研究现状。
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| 关 键 词： | 生物基化学品 琥珀酸产生菌 代谢工程 发酵 提取工艺 生物质原料 |
Research Progress on Succinic acid Production by Microbial Fermentation |
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| Zheng Pu,Sun Zhihao,Ni Ye,Liu Xuan.Research Progress on Succinic acid Production by Microbial Fermentation[J].Biotechnology Bulletin,2008(Z1). |
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| Authors: | Zheng Pu Sun Zhihao Ni Ye Liu Xuan |
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| Institution: | The Key Laboratory of Industrial Biotechnology;Ministry of Education;School of Biotechnology;Jiangnan University;Wuxi 214122 |
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| Abstract: | Succinic acid is an important four-carbon intermediate compound,serving as the starting material for producing bulk chemicals.It has a huge market for producing food and pharmaceutical products,surfactants,detergents, green solvents,biodegradable plastics,and feeds ingredients to stimulate animal and plant growth.Based on renewable resources and fixation of greenhouse gas CO_2,succinic acid produced by microbial fermentation has significant environmental advantages and attracted great interests recently.Thi... |
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| Keywords: | Bio-based chemicals Succinate-producing microorganisms Metabolic engineering Fermentation Separation technology Renewable resources |
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