| 重构胚中线粒体命运的研究进展 |
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| 引用本文： | 鞠光伟,杜卫华,郝海生,赵学明,王栋,朱化彬.重构胚中线粒体命运的研究进展[J].生物技术通报,2010(2). |
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| 作者姓名： | 鞠光伟 杜卫华 郝海生 赵学明 王栋 朱化彬 |
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| 作者单位： | 中国农业科学院北京畜牧兽医研究所,北京,100193 |
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| 基金项目： | 农业科技跨越计划，科技支撑课题，中国农业科学院创新团队，基本科研业务费项目 |
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| 摘 要： | 线粒体是哺乳动物细胞中最为重要的细胞器之一,是除细胞核外惟一含有功能性基因组的细胞器,通过氧化磷酸化产生维持细胞正常生理功能的ATP。重构胚中线粒体的命运及线粒体与供体核间的互作关系已越来越成为研究的焦点,综述了同种、异种核移植,ICSI,卵胞质移植及异源线粒体注射后,重构胚中线粒体的命运。
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| 关 键 词： | 哺乳动物 重构胚 线粒体 线粒体命运 |
The Progress of Study on the Fate of Mitochondrion in Reconstructed Embryo |
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| Ju Guangwei,Du Weihua,Hao Haisheng,Zhao Xueming,Wang Dong,Zhu Huabin.The Progress of Study on the Fate of Mitochondrion in Reconstructed Embryo[J].Biotechnology Bulletin,2010(2). |
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| Authors: | Ju Guangwei Du Weihua Hao Haisheng Zhao Xueming Wang Dong Zhu Huabin |
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| Institution: | Ju Guangwei Du Weihua Hao Haisheng Zhao Xueming Wang Dong Zhu Huabin(Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100193) |
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| Abstract: | Mitochondrion is one of the most important organelles in mammals,which is the exclusive organelle that contains functional genome except nucleus,producing ATP to maintain cells'normal function through oxidative phosphorylation.The fate of the mitochondrion of the reconstructed embryo and the interaction between mitochondrion and the donor nucle is becoming the focus of the research.This article summarizes the fate of the mitochondrion in the reconstructed embryo after nuclear transplantation between homogen... |
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| Keywords: | Mammal Reconstructed embryo Mitochondrion Fate of mitochondrion |
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