| 法呢基焦磷酸(FPP)的生物合成及其分子调控 |
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| 引用本文： | 陈新,李玲玲,吕慧贞,刘庆忠,张元湖.法呢基焦磷酸(FPP)的生物合成及其分子调控[J].生物技术通报,2007,0(2):67-71. |
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| 作者姓名： | 陈新 李玲玲 吕慧贞 刘庆忠 张元湖 |
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| 作者单位： | 1. 山东农业大学,作物生物学重点实验室,泰安,271018
2. 山东省果树研究所,泰安,271000 |
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| 摘 要： | 法呢基焦磷酸合酶作为异戊二烯途径中的重要调节酶,是许多萜类物质的合成前体。FPS的cDNA克隆在许多生物体中也已得到了分离并进行了表达特性研究。从FPP的生物合成途径入手,对FPP生物学特性、FPS酶基因调控的相关信息进行了综述,同时对FPS在基因工程方面的应用进行了展望。
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| 关 键 词： | 法呢基焦磷酸 生物学功能 分子调控 |
| 修稿时间： | 2006-10-30 |
The Biosynthetic Pathway and Molecular Regulation of Farnesyl Diphosphate (FPP) |
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| Chen Xin,Li Lingling,Lv Huizhen,Liu Qingzhong,Zhang Yuanhu.The Biosynthetic Pathway and Molecular Regulation of Farnesyl Diphosphate (FPP)[J].Biotechnology Bulletin,2007,0(2):67-71. |
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| Authors: | Chen Xin Li Lingling Lv Huizhen Liu Qingzhong Zhang Yuanhu |
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| Institution: | 1.Shandong Agricultural University,State Key Laboratory of Crop Biology, Taian 271018;2Shandong Institute of Pomology, Taian 271000 |
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| Abstract: | In the isoprenoid biosynthesis pathway,farnesyl diphosphate synthase(FPS,EC2.5.1.1/EC2.5.1.10)catalyzes two consecutive condensations of isopentenyl diphosphate with dimethylallyl diphosphate,forming geranyl diphosphate(FPP)which is a common precursor for the biosynthesis of sterols,dolichols,mitochondrial electron transfer chain components,prenylated proteins and a wide range of secondary sesquiterpenoids.Recently,cDNAs encoding FPS had been isolated from a number of plant species.In the paper,the biosythasis pathway and molecular regulation of farnesyl diphosphate were reviewed,and progress of FPS applied in genetic engineering was also prospected. |
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| Keywords: | Farnesyl diphosphate Biological function Molecular regulation |
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