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丁酸调控幼龄反刍动物瘤胃上皮发育研究进展
引用本文:王璐,刘理想,孙大明,刘军花.丁酸调控幼龄反刍动物瘤胃上皮发育研究进展[J].生物技术通报,2020(2):49-57.
作者姓名:王璐  刘理想  孙大明  刘军花
作者单位:国家动物消化道营养国际联合研究中心江苏省消化道营养与动物健康重点实验室南京农业大学消化道微生物研究室;动物科学类国家级实验教学示范中心南京农业大学
基金项目:国家重点研发项目(2018YFD0501900)
摘    要:瘤胃是反刍动物营养物质消化吸收和代谢的重要器官,其发育状态直接影响反刍动物生产性能和健康。初生犊牛和羔羊,瘤胃功能尚未发育完全,不能够充分消化和吸收固体饲料。因此,在幼龄时期,通过营养调控手段促进反刍动物的瘤胃发育对维持动物健康及提高生产性能具有重要意义。丁酸是瘤胃微生物降解植物性饲料的主要产物,也是瘤胃上皮及宿主的重要能量来源。丁酸调控幼龄反刍动物瘤胃上皮发育是一个历久弥新的话题。主要介绍了幼龄反刍动物瘤胃上皮形态及功能的发育以及丁酸调控幼龄反刍动物瘤胃上皮发育的研究进展。

关 键 词:丁酸  短链脂肪酸  瘤胃上皮  幼龄反刍动物

Research Progress of Butyrate Regulating Rumen Epithelial Development in Young Ruminants
WANG Lu,LIU Li-xiang,SUN Da-ming,LIU Jun-hua.Research Progress of Butyrate Regulating Rumen Epithelial Development in Young Ruminants[J].Biotechnology Bulletin,2020(2):49-57.
Authors:WANG Lu  LIU Li-xiang  SUN Da-ming  LIU Jun-hua
Institution:(National Center for International Research on Animal Gut Nutrition,Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health,Laboratory of Gastrointestinal Microbiology,College of Animal Science and Technology,Nanjing Agricultural University,Nanjing 210095;National Experimental Teaching Demonstration Center of Animal Science,Nanjing Agricultural University,Nanjing 210095)
Abstract:Rumen,a very important and specific organ in ruminants,is responsible for feed digestion,nutrient absorption and metabolism,thus its developmental state directly affects animal performance and health. The rumen of newborn calves and lambs has not been well developed,thus it is unable for them to fully digest and absorb solid feed. Therefore,the promotion in rumen development of ruminants through nutritional strategies is vital to maintain animal health and improve production performance. Butyrate,the main end product of rumen microbial fermentation of plant feed,is also the important energy source of rumen epithelia and host. The topic of butyrate regulating rumen epithelial development has lost none of its original charm. This paper mainly introduces the development of rumen epithelial morphology and function and the research progress of butyrate regulating rumen epithelial development in young ruminants.
Keywords:butyrate  volatile fatty acids  rumen epithelium  young ruminant
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