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基因突变的分子检测技术
引用本文:霍金龙,苗永旺,曾养志.基因突变的分子检测技术[J].生物技术通报,2007,0(2):90-97.
作者姓名:霍金龙  苗永旺  曾养志
作者单位:1. 云南农业大学动物科学学院,昆明,650201;云南省版纳微型猪近交系重点实验室,昆明,650201
2. 云南农业大学动物科学学院,昆明,650201
基金项目:国家高技术研究发展计划(863计划)
摘    要:基因突变的分子检测是确定生物性状与某种遗传变异的关系、探讨生物物种内基因的差异、了解生物种间亲缘和进化的关键技术,对群体遗传学和生物分类学研究、遗传病诊断等都有着重要的理论意义和实用价值。因此,对于基因突变的检测方法的研究目前受到广泛关注。对基因突变的形式及其分子检测技术作了全面综述。

关 键 词:基因  基因突变  突变检测
修稿时间:2006-11-06

Molecular Detecting Technology on Gene Mutation
Huo Jinlong,Miao Yongwang,Zeng Yangzhi.Molecular Detecting Technology on Gene Mutation[J].Biotechnology Bulletin,2007,0(2):90-97.
Authors:Huo Jinlong  Miao Yongwang  Zeng Yangzhi
Institution:1.Faculty of Animal Science, Yunnan Agricultural University,Knaming 650201 ;2.Banna Mini-pig Inbred Lines Key Laboratory of Yunna Province ,Knnming 650212
Abstract:The assay of gene mutation is very important for the determination of the relationship between phenotype and nucleic acid mutation,gene polymorphism among individuals of the same species,the homologous and phylogenetic relationship between different species.It is of great significance in the study of the population genetics and taxonomy and genetic diseases diagnosis both theoretically and practically.Therefore,the research of molecular detecting technology on gene mutation has been paid great attention recently.In this paper,the detection techniques used widely for gene mutation and the applications of the methods of gene mutation were reviewed.
Keywords:Gene Gene mutation Mutation detection
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