| 电子显微三维重构技术发展与前沿 |
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| 引用本文： | 张凯,张艳,胡仲军,季刚,孙飞.电子显微三维重构技术发展与前沿[J].生物物理学报,2010(7). |
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| 作者姓名： | 张凯 张艳 胡仲军 季刚 孙飞 |
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| 作者单位： | 中国科学院生物物理研究所;生物大分子国家重点实验室;后勤工程学院基础部; |
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| 基金项目： | 科技部973“蛋白质机器与机制”(2006BC806506),蛋白质研究计划“膜蛋白和蛋白质复合体功能与结构研究”(2006CB911001); 中国科学院知识创新工程重大研究项目“面向蛋白质科学的高性能计算研究”(KGCX1-YW-13); 国家自然科学基金创新群体(30721003)~~ |
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| 摘 要： | 本文对电子显微三维重构技术(也称电镜三维重构,electron microscopy 3D reconstruction)进行简要介绍,并在此基础上对该技术当前研究的发展和前沿进行综述,包括高分辨率电镜三维重构、仪器设备性能突破、自动化数据收集和处理、高性能计算技术应用、二/三维图像处理技术的发展和创新、基于三维重构图的模型计算等方面,最后对电子显微三维重构技术的未来进行了展望。
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| 关 键 词： | 电子显微学 三维重构 自动化 高性能计算 图像处理 结构模建 |
Development and Frontier of Electron Microscopy 3D Reconstruction |
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| ZHANG Kai,ZHANG Yan,HU Zhongjun,Ji Gang,SUN Fei . National Laboratory of Biomacromolecules.Development and Frontier of Electron Microscopy 3D Reconstruction[J].Acta Biophysica Sinica,2010(7). |
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| Authors: | ZHANG Kai ZHANG Yan HU Zhongjun Ji Gang SUN Fei National Laboratory of Biomacromolecules |
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| Institution: | ZHANG Kai1,ZHANG Yan1,HU Zhongjun1,2,Ji Gang1,SUN Fei1 1. National Laboratory of Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China 2. Department of Physics,Logistics Engineering University,Chongqing 401311,China |
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| Abstract: | The technology combining cryo-electron microscopy and three-dimensional reconstruction could be simply called electron microscopy 3D reconstruction and this technology has been developed quickly and applied widely in life science research recently. Here we gave a brief introduction of 3D reconstruction electron microscopy and then reviewed its current development and frontier such as high resolution electron microscopy 3D reconstruction, improved performance and innovation of electron microscopes, automatic... |
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| Keywords: | Electron microscopy 3D reconstruction Automation High performance computing Imaging processing Structure modeling |
| 本文献已被 CNKI 等数据库收录！ |
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