| 多模态分子影像对肝癌进展和血管生成的研究 |
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| 引用本文： | 马喜波,田捷,杨鑫,秦承虎,朱守平,薛贞文.多模态分子影像对肝癌进展和血管生成的研究[J].生物物理学报,2011(4):355-364. |
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| 作者姓名： | 马喜波 田捷 杨鑫 秦承虎 朱守平 薛贞文 |
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| 作者单位： | 中国科学院自动化研究所医学图像处理研究组; |
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| 基金项目： | “973”计划项目(2006CB705700,2011CB707700); 中国科学院知识创新工程重要方向项目(KGCX2-YW-907); 国家自然科学基金项目(81027002,81071205); 中国科学院百人计划; 北京市教委科技重点项目(KZ200910005005)~~ |
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| 摘 要： | 通过对HCCLM3-fLuc-GFP肝癌的进展和血管生成的多模态成像分析,对肝癌细胞在体内生长的适应过程和级数生长特性,分别进行了生物自发荧光成像(bioluminescent imaging,BLI)研究、激发荧光成像(fluorescent imaging,FMI)研究和小动物计算机断层成像(micro-compu...
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| 关 键 词： | 生物自发荧光成像 激发荧光成像 计算机断层成像 肝癌进展 血管生成 |
Research on Liver Tumor Proliferation and Angiogenesis Based on Multi-Modality Molecular Imaging |
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| MA Xibo,TIAN Jie,YANG Xin,QIN Chenghu,ZHU Shouping,XUE Zhenwen Medical Image Processing Group.Research on Liver Tumor Proliferation and Angiogenesis Based on Multi-Modality Molecular Imaging[J].Acta Biophysica Sinica,2011(4):355-364. |
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| Authors: | MA Xibo TIAN Jie YANG Xin QIN Chenghu ZHU Shouping XUE Zhenwen Medical Image Processing Group |
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| Institution: | MA Xibo,TIAN Jie,YANG Xin,QIN Chenghu,ZHU Shouping,XUE Zhenwen Medical Image Processing Group,Institute of Automation,Chinese Academy of Sciences,Beijing 100190,China |
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| Abstract: | To detect the HCC-LM3-fLuc-GFP tumor adaptive and exponential process of tumor progression,bioluminescent imaging(BLI) and fluorescent imaging(FMI) were used to calculate the bioluminescent intensity and fluorescent intensity.The results showed that in the first four days,tumor cells became fewer because of the phagocytosis and decomposition of the macrophage and the trypsins.At about the seventh day,the tumor cells were equal with the number of the cells on the first day.This adaptive process cost about on... |
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| Keywords: | Bioluminescent imaging Fluorescent imaging Micro-computed tomography Liver tumor proliferation Tumor angiogenesis |
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