| 强声对豚鼠动作电位（N_1）潜伏期的影响及永久性阈移（PTS）早期预测指标分析 |
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| 引用本文： | 杜宝东,刘淑芳,王树峰,梁凤和.强声对豚鼠动作电位（N_1）潜伏期的影响及永久性阈移（PTS）早期预测指标分析[J].生物物理学报,1996,12(3):433-436. |
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| 作者姓名： | 杜宝东 刘淑芳 王树峰 梁凤和 |
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| 作者单位： | [1]白求恩医科大学一院耳鼻咽喉科 [2]北京市耳鼻咽喉研究所 |
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| 摘 要： | 用慢性面神经管长期置入电极方法，测试了不同时间，不同强度的白噪声或２．８３ＫＨｚ，强纯音暴露下清醒豚鼠的ＡＰ（Ｎ１）潜伏期，结果发现，暴露后对短声及各频率短纯音反应的ＡＰ（Ｎ１）潜伏期均出现统计学意义的延长者，可作为预测永久性阈移（ＰＴＳ）的一项较理想的指标。
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| 关 键 词： | 听觉 强声 动作电位 永久性阈移 |
OBSERVATION OF CHANGES IN ACTION POTENTIAL (N_1))LATENCY AFTER INTENSIVE SOUND EXPOSURE AND ANALYSIS OF EARLY ASSESSMENT FOR PERMANENT THRESHOLD SHIFTING(PTS) IN GUINEA PIG |
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| Abstract: | The electrode was inseted into Fallopian's canal of Guinea Pigs lasting a long time during the study. The AP(N1) latency in awake Guinea Pigs exposed to white noise or 2.83 KHz tone with various time and intensity was observed systematically. The results shoed that the statistical prolongation of AP(N1) latency in respouse to click and tone bursts after exposure could used as an ideal index of early assessment of PTS (permanent threshold shifting). |
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| Keywords: | White noise Intensive tone Exposure Action potential (AP)Permanent threshold shifting (PTS) |
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