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| 肌肉收缩Hill特性式的理论研究 | |
| 引用本文： | 郭维生,王志坚,刘涓.肌肉收缩Hill特性式的理论研究[J].生物物理学报,2010,26(3):245-250. |
| 作者姓名： | 郭维生 王志坚 刘涓 |
| 作者单位： | 1. 内蒙古大学物理科学与技术学院物理系，呼和浩特 010021； 2. 天水师范学院数理与信息科学学院物理系，甘肃 天水 741001 |
| 基金项目： | 国家自然科学基金;教育部博士点基金 |
| 摘 要： | 从肌球蛋白工作循环的机械化学偶联模型出发，利用化学动力学方法和生物化学热力学原理，结合肌球蛋白单分子实验结果，从能量转化的观点给出了肌肉收缩的Hill特性式，加深了对Hill特性式及肌肉收缩过程中能量转化的理解，在整合肌球蛋白单分子性质与肌肉收缩宏观性质的信息方面做了尝试。 |
| 关 键 词： | 肌肉收缩 肌球蛋白 动力冲程 Hill特性式 |
| 收稿时间： | 2009-12-08 |
Theoretical Study on The Hill Characteristic Equation on Muscle Contraction |
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| GUO Weisheng,WANG Zhijian,LIU Juan.Theoretical Study on The Hill Characteristic Equation on Muscle Contraction[J].Acta Biophysica Sinica,2010,26(3):245-250. | |
| Authors: | GUO Weisheng WANG Zhijian LIU Juan |
| Institution: | 1. Department of Physics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China; 2. Department of Physics, School of Mathematic-Physics and Information Science, Tianshui Normal University, TianShui, Gansu 741001, China |
| Abstract: | Based on the mechanochemical actin-activated myosin ATPase cycle model, utilizing the chemical kinetic method and biochemical thermodynamic principle, taking the experimental results of single myosin into account, Hill characteristic equation on muscle contraction has been deduced in view of energy transduction. This work is helpful for further understanding the Hill characteristic equation and energy transduction in muscle contraction. Another significance of this work is that information regarding myosin properties has been correlated to the functions of muscular fiber. |
| Keywords: | Muscle contraction Myosin Power stroke Hill characteristic equation |
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