| LDL的氧化修饰和氧化修饰LDL的组成和结构变化 |
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| 引用本文： | 陈瑗,周玫.LDL的氧化修饰和氧化修饰LDL的组成和结构变化[J].生物物理学报,1993,9(2):334-340. |
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| 作者姓名： | 陈瑗 周玫 |
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| 作者单位： | 第一军医大学脂质过氧化损伤研究组 广州510515
(陈瑗)，第一军医大学脂质过氧化损伤研究组 广州510515(周玫) |
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| 摘 要： | 与低密度脂蛋白(LDL)相比,氧化修饰LDL(O-LDL)的组成、结构和生物学特性发生了深刻的变化,而组成和结构的改变是生物学特性改变的基础.本文根据最近文献资料.结合我们实验室的工作.对LDL的氧化修饰、O-LDL的组成、结构改变,以及它们的机理作一简要综述.
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| 关 键 词： | 氧化修饰 低密度脂蛋白 结构 |
OXIDATIVE MODIFICATION OF LOW DENSITY LIPOPROTEIN AND THE CHANGES IN MODIFIED LOW DENSITY LIPOPROTEIN |
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| Chen Yuan Zhou Mei.OXIDATIVE MODIFICATION OF LOW DENSITY LIPOPROTEIN AND THE CHANGES IN MODIFIED LOW DENSITY LIPOPROTEIN[J].Acta Biophysica Sinica,1993,9(2):334-340. |
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| Authors: | Chen Yuan Zhou Mei |
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| Institution: | Research Group of Lipoperoxidation Damage. First Military Medical University Guangzhou 510515 |
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| Abstract: | Significant changes of composition, structure and biological property were observed in oxidatively modified LDL (O-LDL) as compared with the native low density lipoprotein (LDL); the changes of the biological property were based on those of the composition and structure in O-LDL. In this paper a brief review for the oxidative modification of LDL. the changes of the composition and structure in O - LDL, and their mechanisms was made. |
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| Keywords: | Oxidatively modified low density lipoprotein Copper ion mediated modification Cell mediated modification Structure Composition |
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