Acyl-CoA: sn-Glycerol-3-Phosphate O-Acyltransferase in Rat Brain Mitochondria and Microsomes |
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| Authors: | Susan M Fitzpatrick Giovanna Sorresso Dipak Haldar |
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| Institution: | Department of Biological Sciences, St. John's University, New York, New York, U.S.A. |
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| Abstract: | Abstract: The subcellular distribution of acyl-CoA: sn -glycerol-3-phosphate O-acyltransferase between brain mitochondria and microsomes was investigated. The activities associated with purified rat brain mitochondrial and microsomal preparations could be distinguished by differences in their acyl-CoA specificity, products of acylation, and sensitivity to N -ethylmaleimide, trypsin, acetone, and polymyxin B. It was concluded that both brain mitochondria and microsomes possess the acyltransferase. |
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| Keywords: | Glycerophosphate acyltransferase Brain Mitochondria Microsomes Polymyxin B Trypsin |
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