Visiting the cell biology of Salmonella infection |
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Authors: | Amit Lahiri Ayan Lahiri Namrata Iyer Priyanka Das Dipshikha Chakravortty |
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Institution: | 1. School of Agricultural and Veterinary Sciences, Universidade Estadual Paulista, Jaboticabal, São Paulo 14884900, Brazil;2. Department of Poultry Diseases, Faculty of Veterinary Medicine, Cairo University, Giza Square 12211, Egypt;3. School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Leicestershire LE12 5RD, United Kingdom |
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Abstract: | Salmonella, a Gram-negative facultative intracellular pathogen is capable of infecting vast array of hosts. The striking ability of Salmonella to overcome every hurdle encountered in the host proves that they are true survivors. In the host, Salmonella infects various cell types and needs to survive and replicate by countering the defense mechanism of the specific cell. In this review, we will summarize the recent insights into the cell biology of Salmonella infection. Here, we will focus on the findings that deal with the specific mechanism of various cell types to control Salmonella infection. Further, the survival strategies of the pathogen in response to the host immunity will also be discussed in detail. Better understanding of the mechanisms by which Salmonella evade the host defense system and establish pathogenesis will be critical in disease management. |
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