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组织相容性复合体在实验鸡中的应用
引用本文:高彩霞,韩凌霞,韩建林.组织相容性复合体在实验鸡中的应用[J].中国实验动物学杂志,2010(2):1-5.
作者姓名:高彩霞  韩凌霞  韩建林
作者单位:[1]中国农业科学院哈尔滨兽医研究所实验动物中心,哈尔滨150001 [2]甘肃农业大学动物科学技术学院,兰州730070 [3]中国农业科学院国家家畜研究所畜禽牧草遗传资源联合实验室,北京100094
摘    要:鸡主要组织相容性复合体(MHC)基因位于鸡16号染色体上,具有高度的多态性。现已发现,不同MHC-B单倍体对各种疾病的抗性不同。本文主要介绍了鸡MHC的结构特点、鸡MHC与抗病性的关系、鸡MHC检测方法的研究进展以及其在鸡抗病育种中的应用前景。

关 键 词:鸡MHC  抗病育种  遗传质量控制

Application of Major Histocompatibility Complex in Laboratory Chickens
GAO Cai-xia,HAN Ling-xia,HAN Jian-lin.Application of Major Histocompatibility Complex in Laboratory Chickens[J].Chinese Journal of Laboratory Animal Science,2010(2):1-5.
Authors:GAO Cai-xia  HAN Ling-xia  HAN Jian-lin
Institution:1.Laboratory Animal Center of Harbin Veterinary Research Institute,CAAS,Harbin 150001,China; 2.College of Animal Science and Technology of Gansu Agricultural University,Lanzhou 730070;3.CAAS-ILRI Joint Laboratory of Livestock and Forage Genetic Resources,Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100094)
Abstract:Chicken major histocompatibility complex(MHC) has been a research focus for its high polymorphism and close relation with varying resistance against diseases.It is located on a microchromosome(chromosome 16).It has been found that it has different resistance against diseases for different B haplotypes.The article gives a detailed introduction about structural characteristics,relation to diseases resistance,the progress in detection methods of chicken MHC,and the prospect of application of MHC in molecular breeding for disease resistance in chickens.
Keywords:Chicken MHC  Breeding  disease resistance  Genetic quality control
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