| SD大鼠麻醉后生化指标变化 |
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| 引用本文： | 谭剑斌,陈瑞仪,胡帅尔.SD大鼠麻醉后生化指标变化[J].中国实验动物学杂志,2008(1):43-45. |
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| 作者姓名： | 谭剑斌 陈瑞仪 胡帅尔 |
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| 作者单位： | 广东省疾病预防控制中心 |
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| 摘 要： | 目的观察SD大鼠麻醉后生化指标的变化。方法50只2月龄SPF级SD种大鼠，雄性28只，雌性22只，每鼠空腹16h，分别在麻醉后0、5、10和20min采血，检测血清ALT、AST、GLU、BUN、TP、ALB、AKP、CREA、CHOL、TG。结果随麻醉时间的延长，SD大鼠的生化指标有不同程度的变化。结论规范麻醉采血操作，缩短SD大鼠麻醉后等待采血的时间可减少生化指标的波动。
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| 关 键 词： | 麻醉 生化指标 戊巴比妥钠 SD大鼠 |
Changes of Biochemistry Indexes in SD Rats after Anesthesia |
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| TAN Jian-bin,CHEN Rui-yi,HU Shuai-er.Changes of Biochemistry Indexes in SD Rats after Anesthesia[J].Chinese Journal of Laboratory Animal Science,2008(1):43-45. |
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| Authors: | TAN Jian-bin CHEN Rui-yi HU Shuai-er |
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| Institution: | (Department of Toxicology, Center for Disease Control and Prevention of Guang Dong Province, Guang Zhou 510300, China) |
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| Abstract: | Objective To observe the changes of biochemistry indexes in SD rats after anesthesia. Methods 50 SPF SD rats aged 2 months, 28 males and 22 females were collected blood in 0,5,10,20min after anesthesia, and serum ALT,AST,GLU, BUN ,TP,ALB ,AKP, CREA, CHOL, TG were detected after fasting of 12 hours. Results The biochemistry indexes in SD rats varied as anaesthetic time increases. Conclusion Standaring the blood collecting operation, and reducing the time to wait for collecting blood in postanesthesia SD rats can decrease the changes of biochemistry indexes. |
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| Keywords: | Anaesthesia Biochemistry index Pentobarbital Sodium SD rats |
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