| HIV/AIDS患者CD4水平对甲状腺功能影响的比较研究 |
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| 引用本文： | 张彤,焦艳梅,张洪海,陈俊梅,孙桂珍,吴昊.HIV/AIDS患者CD4水平对甲状腺功能影响的比较研究[J].中国实验动物学杂志,2008(12):32-33. |
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| 作者姓名： | 张彤 焦艳梅 张洪海 陈俊梅 孙桂珍 吴昊 |
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| 作者单位： | 首都医科大学附属北京佑安医院,北京100069 |
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| 基金项目： | 人类免疫缺陷病毒生物学和免疫应答机制研究（973项目,2006CB504201）. |
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| 摘 要： | 目的观察HIV/AIDS患者甲状腺功能的变化,了解HIV对内分泌的影响。方法检测168例HIV/AIDS患者TT4、TT3、FT4、FT3、TSH,并分析不同CD4水平对甲状腺功能影响。结果HIV/AIDS患者甲状腺功能可保持正常,但低CD4组的FT3、TSH水平低于高CD4组。结论HIV/AIDS患者甲状腺功能可保持正常,但HIV感染不同阶段会对内分泌系统有一定影响。HIV感染对甲状腺影响的具体机制尚不十分清楚,利用动物模型进行进一步研究非常必要。
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| 关 键 词： | HIV/AIDS 甲状腺功能 CD4 |
Effect of CD4 on the Thyroid Function in 168 Cases of HIV/AIDS Patients |
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| ZHANG Tong,JIAOYan-mei,ZHANG Hong-hai,CHEN Jun-mei,SUN Gui-zhen,WU Hao.Effect of CD4 on the Thyroid Function in 168 Cases of HIV/AIDS Patients[J].Chinese Journal of Laboratory Animal Science,2008(12):32-33. |
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| Authors: | ZHANG Tong JIAOYan-mei ZHANG Hong-hai CHEN Jun-mei SUN Gui-zhen WU Hao |
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| Institution: | (Beijing You-an Hospital Affiliated to Capital University of Medical Science, 100069) |
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| Abstract: | Objective To observe the change of thyroid function in HIV/AIDS patients and to understand the impact of HIV on the hormonal function. Methods To detect TT4, TI3, FT4, FT3 and TSH in 168 HIV/AIDS patients, and analyze the effect of different CD4 levels on the thyroid function. Results HIV/AIDS patients could maintain normal thyroid function, the level of PT3 and TSH was higher in the low CD4 group compared with the high CD4 group. Conclusion HIV/AIDS patients can maintain normal thyroid function. However, different stages of HIV infection have some impact on the endocrine system. |
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| Keywords: | HIV/AIDS Thyroid function CD4 |
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