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Epinephrine potentiates activation of human platelets by low density lipoproteins
Authors:Valery N Bochkov  Tatyana A Voino-Yasenetskaya  Vsevolod A Tkachuk
Institution:Institute of Experimental Cardiology, Cardiology Research Center, Moscow, U.S.S.R.
Abstract:Low density lipoproteins activate phosphoinositide turnover, increase free cytoplasmic calcium concentration and stimulate phosphorylation of 20- and 47-kDa proteins in blood platelets. All these effects are substantially potentiated by epinephrine.
Keywords:Platelet activation  LDL  Epinephrine  Atherosclerosis
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