Improvement of nisin production in pH feed-back controlled,fed-batch culture by <Emphasis Type="Italic">Lactococcus lactis</Emphasis>subsp<Emphasis Type="Italic">. lactis</Emphasis> |
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Authors: | Wenhua Lv Wei Cong Zhaoling Cai |
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Institution: | (1) State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, P.O. Box 353, Beijing, 100080, P.R. China |
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Abstract: | Nisin production by Lactococcus lactis subsp. lactisin fed-batch culture was doubled by using a pH feed-back controlled method. Sucrose concentration was controlled at 10 g l–1 giving 5010 IU nisin ml–1 compared to 2660 IU nisin ml–1 in batch culture. |
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Keywords: | fed-batch culture Lactococcus lactissubsp lactis nisin pH feed-back |
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