宁夏石砚子墓地颅骨缺损个体的古病理学

本文对出土于宁夏东汉时期的石砚子墓地中一例罕见颅骨病理性损伤个体进行了古病理学诊断分析,该男性个体颅骨上可见不规则形大面积骨质破坏,累及额骨、左侧顶骨、左侧颞骨以及右侧顶骨,缺损周缘可见成骨性、溶骨性反应混合特征,呈向内、外翻卷状,边缘伴有骨膜反应,颅内壁可见较深血管压迹。通过CT影像分析骨骼损伤形态、骨骼损伤区域特征,并结合临床医学资料进行鉴别诊断,排除了朗格汉斯细胞组织细胞增生症、骨血管瘤、Gorham-Stout综合征、骨髓瘤和非特异性感染,推测该病例的病理诊断为甲状腺癌导致的继发性颅骨转移癌。

Paleopathological study on the skeleton with cranial lesion from the Shiyanzi Cemetery in Ningxia

This study reports a paleopathological differential diagnosis on the skeleton from Shiyanzi Cemetery site of Han Dynasty(2040 BP) in Ningxia. This specimen shows bone lesion on most part of the calvarium. Margins of lesion demonstrate scalloped borders with osteoblastic marginal uplift. The irregular and inward to outward-like beveled margins shows a possible neoplasm from the inside out. The combination of macroscopic observation and CT scanning provides more comprehensive information about ancient human disease and improves the credibility of diagnosis. According to the previous clinical reports, based on the morphology, distribution of the lesion, this individual may suffered from a severe metastatic carcinoma.