九个汉族群体和四个少数民族群体中腺苷酸激酶的遗传多态性

用淀粉凝胶电泳及特异的染色方法，调查了我国九个汉族和四个少数民族群体的腺苷酸激酶-1(AK1)的遗传多态性在这十三个群体中AK1*2频率都远低于AK1*1频率，未达到0.01的多态水平，分别为：兰州汉族0.0096，郑州汉族0.0023，呼和浩特汉族0.0024，西安汉族0.0025，漳州汉族0.0024，羌族0.0024；而在广东客家人、成都汉族、哈尔滨汉族、贵阳汉族以及哈尼族、瑶族、布依族中均为0。在兰州汉族群体中观察到国内第一例AK1*2-2表型。

ADENYLATE KINASE POLYMORPHISM IN NINE HAN SUBPOPULATIONS AND FOUR MINORITIES IN CHINA

By using starch gel electrophoresis and specific staining method, the polymorphism of adenylate kinase-1(AK1) was investigated in nine Han subpopulations and four minorities. In all of the thirteen subpopulations studied , the frequency of AK1 * 2 is less than 0.01 and far lower than that of AK1 * 1. The values of AK1 * 2 were:060096 for Lanzhou Han, 060023 for Zhengzhou Han, 0.0024 for Xi'an Han ,0.0024 for Qiang ethnic group, and it is zero in Chengdu Han, Harbin Han, Guiyang Han and Hakka in Guangdong Province ,as well as in Hani ,Yao, Bouyei ethnic groups. One case of phenotype AK1 * 2-2 was observed in Lanzhou Han subpopulation and this is the first case observde among Chinese.