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| HSP90 mRNA在胃癌和大肠癌中表达的研究 | |
| 引用本文： | 薄爱华,戴洁,李曙光,左东升,陈秀玲,杨燕君,苏华,白丽娜,张晓丽,邢立强.HSP90 mRNA在胃癌和大肠癌中表达的研究[J].中国组织化学与细胞化学杂志,2005,14(2):213-216. |
| 作者姓名： | 薄爱华 戴洁 李曙光 左东升 陈秀玲 杨燕君 苏华 白丽娜 张晓丽 邢立强 |
| 作者单位： | 1. 河北北方学院实验中心 2. 首都医科大学病理科 3. 河北北方学院附属第一医院肿瘤科,张家口,075029 |
| 摘 要： | 目的为探讨胃癌和大肠癌细胞HSP90 mRNA表达的特点.方法利用核酸原位杂交技术,对79例胃肠癌组织进行检测.结果表明HSP90 mRNA在胃癌和大肠癌中的阳性率分别为55.56%(15/27)和69.23%(36/52).mRNA表达与病理类型、分化程度和有否淋巴结转移有相关性.结论 HSP90 mRNA在胃肠癌中有较高表达,检测HSP90 mRNA可以作为提示预后的重要临床指标. |
| 关 键 词： | 胃癌 大肠癌 原位杂交 热休克蛋白90 |
| 修稿时间： | 2004年10月12 |
THE STUDY OF HSP90 mRNA EXPRESSION IN GAWTRIC CANCER AND LARGE INTESTINE CARCINOMA |
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| Bo Aihua,Dai Jie,Li Shuguan,Chen Xiuling,Zhang Jianglan,Yang Yanjun,Su Hua,Bai Lina,Zhang Xiaoli,Xing Liqiang.THE STUDY OF HSP90 mRNA EXPRESSION IN GAWTRIC CANCER AND LARGE INTESTINE CARCINOMA[J].Chinese Journal of Histochemistry and Cytochemistry,2005,14(2):213-216. | |
| Authors: | Bo Aihua Dai Jie Li Shuguan Chen Xiuling Zhang Jianglan Yang Yanjun Su Hua Bai Lina Zhang Xiaoli Xing Liqiang |
| Abstract: | Objective To study the expression of HSP90 mRNA in gastric cancer and large intestine cancer. Methods The 79 cases of gastrointestinal cancer were examined by in situ hybridization methods. Results The positive expression rate of HSP90 mRNA 55.56% (15/27) and 69.23% (36/52) respectively in gastric cancer and large intestine cancer. The expression of HSP90 mRNA was correlated with pathologic type, differentiation degree and lymph node metastasis. Conclusion HSP90 mRNA may sevre as an important clinical index for the prognosis of gastric and large intestine cancer. |
| Keywords: | Gastric cancer Large intestine cancer In situ hybridization Heat shock protein 90 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |