An in-depth Comparison of the Pediatric and Adult Urinary N-glycomes |
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Institution: | Department of Urology, Boston Children''s Hospital and Harvard Medical School, Boston, Massachusetts, USA |
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Abstract: | Highlights- ?N-glycan patterns are distinct in pediatric and adult urine.
- ?Sex differences of N-glycans are much larger in adults.
- ?Pediatric urine has almost no sex differences in N-glycan levels.
- ?In adults, the majority of N-glycans were more abundant in males.
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Keywords: | Glycomics urine analysis mass spectrometry quantification N-glycosylation adult glycome nanoLC-MS/MS pediatric urinary |
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