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An in-depth Comparison of the Pediatric and Adult Urinary N-glycomes
Institution:Department of Urology, Boston Children''s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Abstract:
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Highlights
  • ?N-glycan patterns are distinct in pediatric and adult urine.
  • ?Sex differences of N-glycans are much larger in adults.
  • ?Pediatric urine has almost no sex differences in N-glycan levels.
  • ?In adults, the majority of N-glycans were more abundant in males.
Keywords:Glycomics  urine analysis  mass spectrometry  quantification  N-glycosylation  adult  glycome  nanoLC-MS/MS  pediatric  urinary
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