Differential pattern of spinal sympathetic outflow in response to stimulation of the caudal medullary raphe |
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| Authors: | Larsen P D Zhong S Gebber G L Barman S M |
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| Institution: | Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan 48824, USA. |
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| Abstract: | In urethan-anesthetized cats, frequency domain analysis was used to explore the mechanisms of differential responses of inferior cardiac (CN), vertebral (VN), and renal (RN) sympathetic nerves to electrical stimulation of a discrete region of the medullary raphe (0-2 mm caudal to the obex). Raphe stimulation in baroreceptor-denervated cats at frequencies (7-12 Hz) that entrained the 10-Hz rhythm in nerve activity decreased CN and RN activities but increased VN activity. The reductions in CN and RN discharges were associated with decreased low-frequency (
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