Ultraviolet-mediated antibiotic activity of thiophene compounds of Tagetes |
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| Authors: | GFQ Chan GHNeil Towers JC Mitchell |
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| Institution: | 1. Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada;2. Department of Botany, The University of British Columbia, Vancouver, Canada;3. Division of Dermatology, The University of British Columbia, Vancouver, Canada |
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| Abstract: | Two intensely mauve UV fluorescent compounds isolated from Tagetes root were found to be phototoxic to Candida albicans. By chromatography on alumina followed by gel filtration on Sephadex LH-20, the compounds were identified as 5-(3-buten-1-ynyl)-2,2′-bithienyl and α-terthienyl. |
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| Keywords: | Compositae phototoxicity thiophenes 5-(3-buten-1-ynyl)-2 2′-bithienyl α-terthienyl |
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