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Geranylated phenolic constituents from the fruits of Artocarpus nobilis
Authors:Jayasinghe Lalith  Rupasinghe G Kalinga  Hara Noriyuki  Fujimoto Yoshinori
Institution:Institute of Fundamental Studies, Hantana Road, Kandy, Sri Lanka. lalith@ifs.ac.lk
Abstract:Chemical investigation of the combined dichloromethane and ethyl acetate extracts of the fruits of Artocarpus nobilis, furnished four new geranylated phenolic constituents, 2,4,4'-trihydroxy-3-(2E)-5-methoxy-3,7-dimethylocta-2,6-dienyl]chalcone (4), 1-(3,4-dihydro-3,5-dihydroxy-2-methyl-2-(3-methyl-2-butenyl)-2H-1-benzopyran-6-yl-3-(4-hydroxyphenyl)-2(E)-propen-1-one (5), 8-geranyl-3',4',7-trihydroxyflavone (8), 3'-geranyl-4',5,7-trihydroxyflavanone (9), together with known related compounds, xanthoangelol (1), xanthoangelol B (2), 3-geranyl-2,3',4,4'-tetrahydroxychalcone (3), lespeol (6), 8-geranyl-4',7-dihydroxyflavanone (7), and isonymphaeol-B (10). Compounds 3, 8 and 10 showed strong antioxidant activity against DPPH radical by spectrophotometric method.
Keywords:Artocarpus nobilis  Moraceae  Chalcones  Dihydrochalcones  Flavones  Flavonoids  Antioxidant  DPPH radical
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