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Ingenane diterpenoids from Euphorbia esula |
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| Authors: | Lu Zhi-Qiang Yang Min Zhang Jin-Qiang Chen Guang-Tong Huang Hui-Lian Guan Shu-Hong Ma Chao Liu Xuan Guo De-An |
| Institution: | Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Guo Shoujing Road 199, Zhangjiang, Shanghai 201203, PR China. |
| Abstract: | An extensive study of metabolites present in Euphorbia esula led to isolation of 16 ingenane diterpenoids 1-16 together with the known ingenane derivative 17 and four known cycloartane triterpenoids. Their structures were elucidated on the basis of spectroscopic studies and comparison with known related compounds. All the compounds were assayed for their inhibitory activity against human HeLa cervical cancer cell line. |
| Keywords: | Euphorbia esula Euphorbiaceae Diterpenoids Ingenane |
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