| 核移植重构胚染色体重塑的分析研究进展 |
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| 引用本文： | 潘晓燕,王正朝,王锋,郭志勤.核移植重构胚染色体重塑的分析研究进展[J].四川动物,2007,26(4):958-960. |
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| 作者姓名： | 潘晓燕 王正朝 王锋 郭志勤 |
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| 作者单位： | 1. 南京农业大学动物胚胎工程技术中心,南京,210095
2. 新疆畜牧科学院,农业部家畜繁育生物技术重点开放实验室 |
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| 摘 要： | 重构胚核染色体重塑对于核移植的成功是必要的。供体核在卵胞质内将会发生一系列的形态学变化,包括核膜破裂、成熟前的染色体凝集,然后重新形成新的核结构,指导着整个胚胎的发育过程。本综述对发生在核移植重构胚染色体中的生物学事件进行了简要阐述。
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| 关 键 词： | 核移植 染色体 重塑 |
| 文章编号： | 1000-7083（2007）04-0958-03 |
| 修稿时间： | 2006-05-31 |
Chromatin Remodeling in Embryos Reconstructed by Somatic Nuclear Transfer |
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| PAN Xiao-yan,WANG Zheng-chao,WANG Feng,GUO Zhi-qin.Chromatin Remodeling in Embryos Reconstructed by Somatic Nuclear Transfer[J].Sichuan Journal of Zoology,2007,26(4):958-960. |
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| Authors: | PAN Xiao-yan WANG Zheng-chao WANG Feng GUO Zhi-qin |
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| Institution: | 1. Center of Animal Embryo Engineering and Technology, Nanjing Agricutrual University, Nanjing 210095; 2. Key Laboratory of Animal and Veterinary Biotechnology of M0A |
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| Abstract: | Extensive remodeling of chromosomal architecture is critical for animal cloning. The donor nuclei introduced into enucleated oocytes underwent nuclear envelope breakdown,premature chromosome condensation and then formed new nuclei,directing the whole development of the embryos.This review summarizes observations in morphological changes of chromosomes from cloning that reveal some of the likely causes for the present inefficiency.These observations are providing new protocols that could improve the overall success of cloning. |
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| Keywords: | nuclear transfer chromosome remodel |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
